Syndax Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidate includes Revuforj (revumenib), a menin inhibitor for the treatment of relapsed or refractory (R/R) acute leukemia; and Niktimvo (axatilimab-csfr), a colony stimulating factor-1 receptor blocking antibody to treat chronic graft-versus-host disease. The company is also developing revumenib for the treatment of R/R acute myeloid leukemia (AML) with a nucleophosmin 1 mutation (mNPM1) and in combination with standard-of-care agents in mNPM1 AML or KMT2Ar acute leukemia, as well as for metastatic colorectal cancer; axatilimab to treat idiopathic pulmonary fibrosis; and Entinostat, a Class 1 HDAC inhibitor. It has an agreement with Eddingpharm International Company Limited for licensing, development, and commercialization of Entinostat. Syndax Pharmaceuticals, Inc. was incorporated in 2005 and is headquartered in New York, New York.
AML Breakthrough | Syndax's Revuforj shows promise in KMT2A-rearranged AML treatment, with FDA approval expected by December 2024, potentially reshaping the market |
Dual-Drug Strategy | Explore Syndax's two-pronged approach with Revuforj for AML and FDA-approved Niktimvo for cGVHD, positioning the company for growth in oncology |
Financial Outlook | Despite current losses, Syndax maintains a strong cash position through 2026, with analyst price targets ranging from $16 to $51, suggesting potential upside |
Market Challenges | Delve into Syndax's competitive landscape, regulatory hurdles, and strategies to overcome negative EPS forecasts in the evolving personalized medicine market |
Metrics to compare | SNDX | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipSNDXPeersSector | |
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P/E Ratio | −2.6x | −0.6x | −0.5x | |
PEG Ratio | 0.14 | −0.01 | 0.00 | |
Price/Book | 4.1x | 2.0x | 2.6x | |
Price / LTM Sales | 20.1x | 12.2x | 2.9x | |
Upside (Analyst Target) | 272.5% | 326.8% | 50.4% | |
Fair Value Upside | Unlock | 19.0% | 9.1% | Unlock |