CRISPR Therapeutics AG, a gene editing company, focuses on developing gene-based medicines for serious human diseases using its Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform. The company’s CRISPR/Cas9 is a revolutionary technology for gene editing which is the process of precisely altering specific sequences of genomic DNA. It has a portfolio of therapeutic programs across a range of disease areas, including hemoglobinopathies, CAR T cell therapies, in vivo, and type 1 diabetes, as well as develops investigational CAR T programs, including an autologous, gene-edited CAR T program targeting glypican-3 (GPC3) for the potential treatment of solid tumors. The company’s lead product candidate is CASGEVY, an ex vivo CRISPR/Cas9 gene-edited cell therapy for treating patients suffering from transfusion-dependent beta-thalassemia, severe sickle cell disease (SCD), and hemoglobinopathies in which a patient’s hematopoietic stem and progenitor cells are edited to produce high levels of fetal hemoglobin in red blood cells. It also develops CAR T cell therapies, including CTX112 targeting cluster of differentiation 19 (CD19) and CTX131 targeting CD70 for oncology and autoimmune indications; CTX310 and CTX320, in vivo gene editing to address the cardiovascular disease by disrupting the validated targets angiopoietin-like protein 3 and lipoprotein; and CTX211, an allogeneic, gene-edited, hypoimmune stem cell-derived product candidate for the treatment of T1D. It has strategic partnerships with Vertex Pharmaceuticals Incorporated, Nkarta, Inc., and Capsida Biotherapeutics. CRISPR Therapeutics AG was incorporated in 2013 and is headquartered in Zug, Switzerland.
Casgevy's Launch | Explore CRISPR Therapeutics' groundbreaking gene therapy Casgevy, its market potential, and early adoption rates across authorized treatment centers globally |
Pipeline Potential | Delve into CRISPR's diverse clinical pipeline, including promising CAR-T therapies and in vivo gene editing programs poised to reshape treatment landscapes |
Financial Outlook | Analyst price targets for CRISPR range from $53 to $105, reflecting varied perspectives on the company's commercial prospects and pipeline potential |
Competitive Edge | Uncover how CRISPR Therapeutics maintains its leadership in gene editing amid fierce competition, balancing innovation with market positioning challenges |
Metrics to compare | CRSP | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipCRSPPeersSector | |
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P/E Ratio | −8.8x | −0.6x | −0.5x | |
PEG Ratio | 0.07 | 0.00 | 0.00 | |
Price/Book | 1.7x | 0.9x | 2.6x | |
Price / LTM Sales | 86.8x | 8.7x | 2.9x | |
Upside (Analyst Target) | 114.5% | 509.8% | 57.8% | |
Fair Value Upside | Unlock | 25.8% | 10.2% | Unlock |