Janus Detroit Street Trust - Janus Henderson Mortgage-Backed Securities ETF is an exchange traded fund launched and managed by Janus Henderson Investors US LLC. The fund invests in fixed income markets of the United States. It primarily invests in U.S. dollar denominated investment grade mortgage-related securities issued by the U.S. government and its agencies such as the Government National Mortgage Association, the Federal National Mortgage Association or the Federal Home Loan Mortgage Corporation and are rated Baa3/BBB- or higher. The fund invests in securities with varying maturities. It employs fundamental analysis with bottom-up security picking approach to create its portfolio. The fund seeks to benchmark the performance of its portfolio against the Bloomberg U.S. Aggregate Bond Index and the Bloomberg U.S. Mortgage Backed Securities Index. Janus Detroit Street Trust - Janus Henderson Mortgage-Backed Securities ETF was formed on September 12, 2018 and is domiciled in the United States.