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Karyopharm Therapeutics Inc (KPTI)

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1.080 +0.050    +4.85%
06:00:01 - Closed. Currency in USD ( Disclaimer )
After Hours
1.070
-0.010
-0.926%
9:30:27 - Real-time Data
  • Volume: 1,554,000
  • Bid/Ask: 0.000 / 0.000
  • Day's Range: 1.055 - 1.150
Type:  Equity
Market:  United States
Karyopharm 1.080 +0.050 +4.85%

Karyopharm Therapeutics Inc Company Profile

 
Get an in-depth profile of Karyopharm Therapeutics Inc, including a general overview of the company's business and key management, as well as employee data and location and contact information.
IndustryBiotechnology & Medical Research
SectorHealthcare
Employees

385

Equity Type

ORD

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). It also developing Selinexor for treating hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, myelofibrosis, and DLBCL; and ELTANEXOR for treating Myelodysplastic Neoplasms, as well as verdinexor, KPT-9274, and IL-12 compounds. The company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor, eltanexor, and KPT-9274 for the treatment and/or prevention of human oncology indications, as well as verdinexor for the diagnosis, treatment, and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. Further, it has a collaboration with Bristol Myers Squibb company to evaluate novel cereblon E3 ligase modulator agent mezigdomide in combination with Selinexor in patients with relapsed/refractory multiple myeloma. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Contact Information

Address 85 Wells Avenue Suite 210
Newton, 02459-3298
United States
Phone 617 658 0600
Fax -

Top Executives

Name Age Since Title
Garen G. Bohlin 77 2013 Independent Director
Barry E. Greene 61 2013 Lead Independent Director
Deepika Rachel Pakianathan 59 2013 Independent Director
Michael R. Savona - - Member of Scientific Advisory Board
Richard A. Paulson 57 2020 President, CEO & Director
Zhen Su - 2023 Independent Director
Andrew B. Lassman - 2020 Member of Scientific Advisory Board
Christy J. Oliger 54 2020 Independent Director
Chen Schor 52 2020 Independent Director
Andrew Kung - 2020 Member of Scientific Advisory Board
Sharon Shacham 54 2008 Co-Founder & Chairman of Scientific Advisory Board
Mansoor Raza Mirza 63 2010 Clinical Consultant, Member of Scientific Advisory Board & Independent Director
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