Sarepta shares rise on positive Mizuho outlook

Published 27/11/2024, 05:54 am
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On Tuesday, Mizuho (NYSE:MFG) maintained a positive stance on Sarepta Therapeutics (NASDAQ:SRPT), reiterating an Outperform rating with a $200.00 price target. The firm's optimism is fueled by Sarepta's recent global licensing and collaboration agreement with Arrowhead, which is expected to significantly enhance Sarepta's pipeline.

The deal between Sarepta and Arrowhead involves an expansion of Sarepta's mid- and early-stage pipeline with the inclusion of potentially 13 RNAi programs. This includes exclusive worldwide rights to four orphan clinical programs targeting FSHD1, DM1, IPF, and SCA2, as well as three orphan CNS preclinical programs for SCA1, SCA3, and HTT, and up to six IND-ready constructs across skeletal and cardiac muscle, and CNS.

Mizuho highlighted that this collaboration diversifies Sarepta's pipeline beyond gene therapy by utilizing Arrowhead's TRiM platform. This platform is designed to deliver siRNA to specific tissues or cell types, inducing rapid and durable gene knockdown. The move is seen as a strategy to alleviate concerns regarding Sarepta's previously thin pipeline, which has been seen as a significant issue for the company.

Furthermore, the partnership is expected to be a key growth driver for Sarepta, providing multiple avenues for expansion. Management at Sarepta anticipates that the collaboration will lead the company to profitability and positive cash flow in the future.

Closing the announcement, Mizuho reaffirmed their Outperform rating and $200 price target for Sarepta Therapeutics, signaling a confident outlook on the company's growth prospects and financial health.

In other recent news, Arrowhead Pharmaceuticals (NASDAQ:ARWR) and Sarepta Therapeutics have announced a comprehensive licensing and collaboration agreement. This deal will see Arrowhead receiving an immediate $825 million, along with a potential $10 billion in future milestone payments and royalties on product sales. The partnership will grant Sarepta access to Arrowhead's Targeted RNAi Molecule (TRiM™) platform to develop treatments for rare genetic diseases affecting muscles, the central nervous system, and lungs.

InvestingPro Insights

Recent InvestingPro data and tips provide additional context to Mizuho's optimistic outlook on Sarepta Therapeutics (NASDAQ:SRPT). The company's market cap stands at $12.27 billion, reflecting its significant presence in the biotechnology sector. Sarepta's revenue growth is particularly noteworthy, with a 48.45% increase over the last twelve months as of Q3 2024, and a 40.79% quarterly growth in Q3 2024. This robust revenue expansion aligns with Mizuho's positive stance on the company's growth prospects.

An InvestingPro Tip indicates that Sarepta is trading at a low P/E ratio relative to its near-term earnings growth, suggesting potential undervaluation despite its current P/E ratio of 100.6. This could support Mizuho's $200 price target, which implies significant upside potential from the current price.

Another relevant InvestingPro Tip notes that net income is expected to grow this year, which corroborates management's anticipation of future profitability as mentioned in the article. The company's ability to operate with a moderate level of debt, as highlighted by another tip, may provide financial flexibility as it pursues its expanded pipeline through the Arrowhead collaboration.

For investors seeking a more comprehensive analysis, InvestingPro offers 11 additional tips for Sarepta Therapeutics, providing a deeper understanding of the company's financial health and market position.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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