Highlights
- Chimeric is advancing CHM 1301 program to the next stage of preclinical development.
- CHM 1301 is a next generation chlorotoxin (CLTX) chimeric antigen receptor (CAR) NK cell therapy.
- The therapy demonstrated highly promising efficacy in preclinical studies of in vitro models of human ovarian cancer and pancreatic cancer.
- CHM shares charged higher by 7%.
Chimeric Therapeutics Limited (ASX: CHM) shares gained over 7% on 28 November 2023 as the company announced additional information on its earlier update focused on positive in vitro data for CHM 1301.
The next generation CLTX CAR NK cell therapy program is entering the next phase of preclinical development. Under the study, the company plans to use armoured NK cell platform (CHM 0301) that was recently developed.
The study would aim to boost cell potency and resistance against the immunosuppressive solid tumour microenvironment.