C4 Therapeutics appoints Steve Hoerter to board

Published 20/11/2024, 11:06 pm
CCCC
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WATERTOWN, Mass. - C4 Therapeutics, Inc. (NASDAQ:CCCC), a biopharmaceutical firm focused on protein degradation therapeutics, has announced the appointment of Steve Hoerter to its Board of Directors. The move is part of the company's strategic effort to enhance its governance with experienced industry leaders as it progresses its pipeline of novel degraders.

Hoerter brings over 30 years of experience in oncology commercialization to the C4T board. His past roles include President and CEO of Deciphera Pharmaceuticals (NASDAQ:DCPH), which was acquired for $2.4 billion by ONO Pharmaceutical (TADAWUL:2070) in June 2024. At Deciphera, he led the company to global integration and the successful launch of QINLOCK® for gastrointestinal stromal tumors. Hoerter's commercial acumen was also evident during his tenure as Chief Commercial Officer at Agios Pharmaceuticals, where he facilitated the launch of TIBSOVO® and IDHIFA®, treatments for acute myeloid leukemia.

Andrew Hirsch, President and CEO of C4 Therapeutics, expressed enthusiasm for Hoerter's appointment, citing his proven expertise in advancing oncology programs and guiding commercial strategy. Hirsch anticipates that Hoerter's experience will be instrumental as C4T aims to transition into a fully integrated biotechnology company.

Hoerter's career also includes leadership and commercial roles at Clovis Oncology (OTC:CLVSQ), Roche, Genentech, Chiron Corporation, and Eli Lilly and Company (NYSE:LLY). Additionally, he has served on the boards of several pharmaceutical companies, including ORIC Pharmaceuticals, Constellation Pharmaceuticals (NASDAQ:CNST), and Ignyta.

Expressing his eagerness to contribute to C4T's mission, Hoerter highlighted the company's potential to disrupt the treatment landscape with its targeted protein degraders, which are designed to harness the body’s natural protein recycling system to degrade disease-causing proteins.

C4 Therapeutics is advancing targeted oncology programs through clinical studies and is leveraging its proprietary TORPEDO® platform to design and optimize small-molecule medicines for difficult-to-treat diseases. The appointment of Hoerter is a testament to the company's commitment to leadership excellence as it continues to develop new therapies for patients.

This news is based on a press release statement from C4 Therapeutics.

In other recent news, C4 Therapeutics has reported a series of significant developments. The biopharmaceutical company announced the appointment of Paige Mahaney, Ph.D., as its new Chief Scientific Officer, succeeding Stewart Fisher, Ph.D. In addition, the company has amended its stock incentive plan to prohibit repricing without shareholder approval, aligning with a growing trend among public companies to ensure transparency and shareholder input on executive compensation matters.

C4 Therapeutics also reported promising initial data from its Phase 1 trial of CFT1946, a molecule targeting BRAF V600 mutant solid tumors. The trial demonstrated successful degradation of the BRAF V600E protein across various doses. Furthermore, the company achieved a milestone in its collaboration with Biogen (NASDAQ:BIIB), triggering an $8 million payment, which underscores the productivity of their TORPEDO® platform.

Analysts from BMO Capital Markets and Stifel have maintained positive ratings on the company, highlighting the potential of CFT1946. Additionally, the company received approval from the Chinese New Medical (TASE:PMCN) Products Agency for a clinical trial of CFT8919, a treatment for patients with EGFR L858R-mutated non-small cell lung cancer, following a partnership with Betta Pharmaceuticals. These are the latest developments in the company's operations.

InvestingPro Insights

As C4 Therapeutics (NASDAQ:CCCC) bolsters its board with industry veteran Steve Hoerter, investors should consider some key financial metrics that shed light on the company's current position. According to InvestingPro data, C4 Therapeutics has a market capitalization of $292.94 million, reflecting its status as a smaller player in the biotech space. The company's revenue for the last twelve months as of Q3 2023 stood at $33.67 million, with an impressive year-over-year growth rate of 65.45%.

Despite this growth, InvestingPro Tips highlight that C4 Therapeutics is "quickly burning through cash" and is "not profitable over the last twelve months." These factors are crucial for investors to consider, especially given the company's focus on advancing its pipeline of novel degraders, which typically requires significant R&D investment.

The stock's performance has been volatile, with InvestingPro data showing a substantial 145.56% price return over the past year. However, more recent trends indicate challenges, with a -19.1% return in the past week and a -34.65% return over the last month. This volatility aligns with another InvestingPro Tip noting that "stock price movements are quite volatile," which is common for emerging biotech companies.

For those interested in a deeper analysis, InvestingPro offers 8 additional tips for C4 Therapeutics, providing a more comprehensive view of the company's financial health and market position. These insights could be particularly valuable as the company aims to leverage Hoerter's experience in commercialization and transition towards becoming a fully integrated biotechnology company.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

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