CytomX Therapeutics, Inc. operates as an oncology-focused biopharmaceutical company that focuses on developing novel conditionally activated biologics localized to the tumor microenvironment. The company utilizes conditional activation platform technology for oncology biologics research and development comprising the validation of targets for antibody-drug conjugates (ADCs), opening therapeutic window for novel T-cell engagers (TCEs) targeting solid tumors, and increasing the therapeutic index for immune modulators, such as cytokines; and PROBODY platform in preclinical research in areas outside of oncology. It also develops CX-904, a T-cell-engaging bispecific antibody targeting the epidermal growth factor receptor (EGFR) on tumor cells and the CD3 receptor on T cells; CX-2051, a conditionally activated ADC for optimizing the therapeutic index for EpCAM-expressing epithelial cancers, including colorectal cancer; and CX-801, an interferon alpha-2b PROBODY cytokine. In addition, the company’s development pipeline comprises CX-2029, a conditional activated ADC targeting CD71; and BMS-986288, a PROBODY version of non-fucosylated ipilimumab. It has strategic collaborations with Amgen, Astellas, Bristol Myers Squibb, Regeneron, and Moderna; and clinical trial collaboration and supply agreement with Merck for the evaluation of CX-801 in combination with anti-PD-1 therapy, KEYTRUDA (pembrolizumab). The company was founded in 2008 and is based in South San Francisco, California.
Pipeline Progress | Explore CytomX's innovative cancer therapies, including EGFRxCD3 for solid tumors and EpCAM ADC for colorectal cancer, with pivotal data expected by 2025 |
Financial Fortification | Learn how CytomX's strategic workforce reduction extends cash runway to Q2 2026, balancing financial prudence with development needs |
Collaborative Potential | Delve into CytomX's partnership with Amgen, offering resource synergies and market credibility, with potential opt-in decision as a major catalyst |
Market Positioning | Analysts set an average price target of $3.50, reflecting optimism in CytomX's probody platform amid the competitive oncology landscape |
Metrics to compare | CTMX | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipCTMXPeersSector | |
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P/E Ratio | 7.7x | −0.6x | −0.5x | |
PEG Ratio | 0.06 | −0.01 | 0.00 | |
Price/Book | 12.8x | 1.2x | 2.6x | |
Price / LTM Sales | 2.2x | 18.2x | 3.0x | |
Upside (Analyst Target) | 145.1% | 316.7% | 48.7% | |
Fair Value Upside | Unlock | 14.2% | 9.2% | Unlock |